|
TMPY-04281
|
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc)
growth hormone receptor
|
Rat
|
HEK293 Cells
|
|
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.4 kDa and the accession number is P16310-1. |
|
TMPJ-00795
|
Growth Hormone Protein, Mouse, Recombinant
Gh1,Somatotropin,Gh,Growth Hormone
|
Mouse
|
E. coli
|
|
Somatotropin(GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. |
|
TMPY-02007
|
GHR/Growth Hormone R Protein, Rat, Recombinant (His)
growth hormone receptor
|
Rat
|
HEK293 Cells
|
|
GHR/Growth Hormone R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is P16310-1. |
|
TMPY-00394
|
Growth Hormone Protein, Human, Recombinant
GHB5,GH-N,GH1,IGHD1B,hGH-N,GHN,Growth hormone
|
Human
|
E. coli
|
|
Growth Hormone Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.1 kDa and the accession number is P01241. |
|
TMPY-01448
|
GHR/Growth Hormone R Protein, Mouse, Recombinant (His)
GHR/BP,growth hormone receptor,GHBP
|
Mouse
|
HEK293 Cells
|
|
GHR/Growth Hormone R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.3 kDa and the accession number is Q3UP14. |
|
TMPJ-00356
|
GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
GHBP,GHR,Somatotropin receptor,growth hormone
|
Mouse
|
HEK293 Cells
|
|
Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead... |
|
TMPY-00977
|
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc)
growth hormone receptor,GHR/BP,GHBP
|
Mouse
|
HEK293 Cells
|
|
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q3UP14. |
|
TMPY-00195
|
Growth Hormone Protein, Human, Recombinant (His)
GH-N,GHN,hGH-N,GH1,IGHD1B,GHB5,GH,growth hormon...
|
Human
|
E. coli
|
|
Growth Hormone Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P01241. |
|
TMPK-00806
|
GHR/Growth Hormone R Protein, Human, Recombinant (His)
GHR/BP,GH receptor,GHBP,GHR
|
Human
|
HEK293 Cells
|
|
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus. |
|
TMPY-00186
|
GHRH Protein, Human, Recombinant (hFc)
GRF,INN,growth hormone releasing hormo...
|
Human
|
HEK293 Cells
|
|
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl... |
|
TMPJ-01471
|
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain
|
Human/Mouse/Rat
|
HEK293 Cells
|
|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm... |
|
TMPY-04853
|
TSHR Protein, Human, Recombinant (His)
TSHR,hTSHR-I,TSH Receptor,LGR3,CHNG1
|
Human
|
Baculovirus Insect Cells
|
|
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
|
TMPK-01246
|
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...
|
Mouse
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPH-03204
|
GHR Protein, Rabbit, Recombinant (His & Myc)
|
Rabbit
|
E. coli
|
|
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941. |
|
TMPH-03112
|
GHR Protein, Pig, Recombinant (His)
|
Sus scrofa (Pig)
|
E. coli
|
|
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Pig, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P19756. |
|
TMPH-02440
|
GHR Protein, Rhesus macaque, Recombinant (His)
|
Rhesus
|
E. coli
|
|
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.2 kDa and the accession number is P79194. |
|
TMPH-02522
|
GHRL Protein, Mouse, Recombinant (His)
|
Mouse
|
E. coli
|
|
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre... |
|
TMPK-00097
|
FGF-21 Protein, Human, Recombinant (mFc & Avi)
FGF-21,PRO10196,FGF21,UNQ3115,成纤维细胞生长因子
|
Human
|
HEK293 Cells
|
|
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is Q9NSA1-1. |
|
TMPY-03443
|
NDRG1 Protein, Human, Recombinant (His)
TARG1,PROXY1,RIT42,NDR1,DRG1,RTP,TDD5,CMT4D,CAP43,NMSL,N-myc...
|
Human
|
E. coli
|
|
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro... |
|
TMPK-00098
|
FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated
成纤维细胞生长因子,FGF-21,UNQ3115,FGF21,PRO10196
|
Human
|
HEK293 Cells
|
|
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number i... |
|
TMPJ-01016
|
INHBC Protein, Human, Recombinant (N-His)
Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...
|
Human
|
E. coli
|
|
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary... |
|
TMPK-00083
|
IGF1/IGF-I Protein, Human, Recombinant (hFc)
IGF1A,胰岛素样生长因子,IBP1,IGF-I,MGF
|
Human
|
HEK293 Cells
|
|
The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes. |
|
TMPH-01530
|
INHBA Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of a... |
|
TMPJ-01015
|
INHBC Protein, Human, Recombinant (C-His)
Activin β-C Chain,Activin Beta-C Chain,Inhibin β C Chain,INH...
|
Human
|
HEK293 Cells
|
|
Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell ... |
|
TMPH-01528
|
IHH Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP). |
|
TMPJ-00080
|
IL-11 Protein, Human, Recombinant (P. pastoris)
白细胞介素,Oprelvekin,Adipogenesis Inhibitory Factor,白介素,IL11,AGI...
|
Human
|
P. pastoris (Yeast)
|
|
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its recepto... |
|
TMPJ-00366
|
GAS6 Protein, Human, Recombinant (hFc)
AXLLG,Gas6,GAS-6,AXLLGAXL stimulatory factor,growth...
|
Human
|
HEK293 Cells
|
|
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ... |
|
TMPJ-00365
|
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
AXLLG,Growth arrest-specific protein 6,AXL receptor...
|
Human
|
HEK293 Cells
|
|
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, plat... |
|
TMPJ-01076
|
FKBP4 Protein, Human, Recombinant (His)
FKBP4,HSP-binding immunophilin,immunophilin FKBP52,FK506-bin...
|
Human
|
E. coli
|
|
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. |
|
TMPH-03158
|
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
|
Porphyromonas gingivalis
|
E. coli
|
|
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig... |
|
TMPY-04999
|
GAS6 Protein, Human, Recombinant (His)
|
Human
|
HEK293
|
|
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ... |
|
TMPK-01244
|
GDF-15 Protein, Mouse, Recombinant (hFc)
PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF15,G...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPJ-00577
|
INSL3 Protein, Human, Recombinant (His)
RLNL,Insulin-like 3,RLF,Leydig insulin-like peptide,INSL3,Re...
|
Human
|
HEK293 Cells
|
|
Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus luteum, trophoblast, fetal membranes and breast. It may act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent.It is a ligand for LGR8 receptor. |
|
TMPK-00665
|
GDF-15 Protein, Cynomolgus, Recombinant (His)
PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...
|
Cynomolgus
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPK-00663
|
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTGF-beta,GDF15,Place...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPK-00198
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF-beta,Placental TG...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00664
|
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG-1,RG-1,P...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00197
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,PDF,PTGF-β,...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-01245
|
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFBPTGF-beta,NAG-1,PT...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPJ-00710
|
ALDH1A2 Protein, Human, Recombinant (His)
RALDH(II),Retinal dehydrogenase 2,RALDH2,ALDH1A2,Retinaldehy...
|
Human
|
E. coli
|
|
Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma... |
|
TMPJ-00271
|
SMAD3 Protein, Human, Recombinant (His & Flag)
SMAD 3,Mothers against DPP homolog 3,hMAD-3,MADH3,JV15-2,SMA...
|
Human
|
E. coli
|
|
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so doing transduce the signal into the nucleus. Receptor-regulated SMAD is an intracellular signal transducer and transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. SMAD3 binds the TRE element in the promoter region of many genes that are regulated... |
|
TMPY-01826
|
Relaxin 1/RLN1 Protein, Human, Recombinant (His)
RLXH1,H1RLX,relaxin 1,bA12D24.3.1,H1,RLN1,bA12D24.3.2
|
Human
|
HEK293 Cells
|
|
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductive hormone 8 years ago, relaxin has been implicated in a number of pregnancy-related functions involving extracellular matrix (ECM) turnover and collagen degradation. It is now becoming evident that relaxin's ability to reduce matrix synthesis and increase ECM degradation has impo... |
|
TMPJ-00715
|
FGF-19 Protein, Human, Recombinant (His)
FGF-19,Fibroblast growth factor 19,FGF19
|
Human
|
E. coli
|
|
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ... |
|
TMPH-02274
|
JAK2 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int... |
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